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It is important to clarify that ALT and AST levels do not reflect the function of the liver, even though in the medical community and in medical publications they commonly, and incorrectly, are referred to as liver function tests.Even in conditions when AST and ALT are very elevated, the liver still may function properly.For example, individuals with acute viral hepatitis A may develop very high AST and ALT levels (sometimes in the thousands of units/liter range), but most people with acute viral hepatitis A recover fully without residual liver disease.Conversely, people with chronic hepatitis C infection typically have only a little elevation in their AST and ALT levels while having substantial liver injury and even advanced scarring of the liver (cirrhosis) from ongoing minor inflammation of the liver.A special court will pronounce judgement on 2G spectrum scam case on December 21.
For example, AST level in serum is elevated in heart attacks or with muscle injury.
Enzymes help to speed up (catalyze) routine and vital chemical reactions in the body.
Among the most sensitive and widely used liver enzymes are the aminotransferases.
It is therefore, not a highly specific indicator of liver injury as its elevation can occur as a result of other injured tissues.
ALT (SGPT) is, by contrast, normally found largely in the liver.
If the liver is injured or damaged, the liver cells spill these enzymes into the blood, raising the AST and ALT enzyme blood levels and signaling liver disease.